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Biomedical Engineering ￨ Applied Mathematics ￨ Mathematical Optimization / Programming
Model Development ￨ Meta-Analysis ￨ Mechanistic Derivation of Model Equations ￨ Simulations
Computation Modeling ￨ Mathematical Analysis ￨ Research ￨ Project Management ￨ Trends Tracking
Recent Ph.D. in Biomedical Engineering and M.S. in Applied Mathematics Graduate who is eager to offer knowledge gained from rigorous academic studies, as well as results-generating research and optimal experimental design experience. Ambitious Self-Starter who specializes in computational modeling of biological networks at the molecular scale. Top Performer who exhibits solutions-centric critical thinking while maintaining cutting-edge skills and up-to-date industry awareness. Excellent Communicator who actively interfaces among research peers, and who leads by example and with ethics and integrity. Member of American Association for the Advancement of Science (AAAS) since 2016.
Career Highlights Include:
Successfully ranking #1 in FORTRAN Programming course.
Offering strong multitasking skills and solid attention-to-detail.
Achieving prestigious Teaching Assistantship and Research Assistantship.
Comprehensively presenting an engaging and details-focused conference paper.
Exhibiting recognition as a quick study who rapidly picks up new scientific concepts.
Publishing two peer-reviewed scientific journal papers, and submitting a third paper for publication.
Ph.D., Biomedical Engineering (3.9 GPA ￨ 2017) Xxxxxx Polytechnic Institute
M.S., Applied Mathematics (3.9 GPA ￨ 2017) Xxxxxx Polytechnic Institute
B.S., Chemical Engineering (Chemical Biomedical Engineering ￨ 3.95 GPA ￨ 2013) Florida State University
Eukaryotic Gene Expression Studies (Three-Week Technical Workshop ￨ 2015) Cold Spring Harbor Laboratory
Research Experience & Accomplishments
Collaborated within a cross-functional team to maximize the production of a high-value chemical in a bioprocess system. Spearheaded the efficient development and implementation of an innovative predictive model to meet core objectives.
Demonstrated skill in proactively resolving an optimal experimental design challenge to maximize parameter accuracy for a mechanistic model of a large molecule signal transduction in inflammation.
Utilized a mechanistic model of T-cell differentiation signaling to resourcefully simulate and maximize predicted expression of translational biomarkers for a comprehensive cell-based treatment of inflammation.
Developed and implemented state-of-the-art modeling and simulation techniques in MATLAB.
Designed software and hardware for a prototype telemedicine device. Wrote software for device in Python.
Publications, Presentations & Inventions
J. A. Jones, A. Sinkoe, et al. Experimental and Computational Optimization of an Escherichia coli Co-culture for the Efficient Production of Flavonoids. Metabolic Engineering, 35, May 2016, pp. 55-63.
A. Sinkoe, J. Hahn. Optimal Experimental Design for Parameter Estimation of an IL-6 Signaling Model. Processes, 5(3), September 2017.
A. Sinkoe, J. Hahn. Maximizing Regulatory T cell Induction in ex vivo Culture via Dynamic Optimal Experimental Design (Submitted October 2017 ￨ Publication Pending).
A. Sinkoe, A. A. Julius, J. Hahn. Identifying Potential Regulatory Interactions of the MAPKAssociated Gene Network. Proceedings of the 5th International Conference on Foundations of Systems Biology in Engineering, Cambridge, August 2015.
A. Sinkoe. U.S. Provisional Patent Application No. 62/576,923: "Telemedicine Diagnosis and Treatment System and Method," Filed October 25, 2017.
Xxxxxx Polytechnic Institute (2013 2017)
Graduate Research Assistant (2013 2017)
Researched computational systems biology. Resolved optimal experimental design problems in practical biological experimental systems. Published peer-reviewed research papers and presented research at international systems biology conferences.
Teaching Assistant (2013 2014 ￨ 2016 2017)
Played a vital role in supporting undergraduate instruction by grading assignments and exams for popular courses, including Modeling & Analysis of Uncertainty, Introduction to Engineering Analysis, Biological Sciences Laboratory, and Modeling of Biomedical Systems. Responded to and resolved student inquiries. Supported tasks required by professors.
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