Yyyyyy x. yyyyyy

Seeking a senior-level Research opportunity at Ventana Medical Systems.

Laboratory Operations ~ Quality Assurance & Quality Control ~ Data Management

Scientific Research ~ Qualitative Analysis ~ Biological & Safety Compliance ~ Staff Training

         15+ years experience in research, development and production laboratory experimentation, with keen interests in cancer diagnostic techniques and technologies.

         Vast laboratory expertise spans molecular biology, histology, immunoassays, cell culture systems, cellular imaging, biochemical purification and assays, and cell-based assays.

         Excel at designing experiments to support broad-scope projects, performing comprehensive data analysis, and compiling technical reports, summaries and quantitative analyses.

         Adept at independently devising methods, techniques and evaluation criteria for obtaining results.

         Well-versed in lab safety regulations including hazardous materials management and OSHA compliance.

         Advanced ability to understand and communicate scientific information, work in cross-disciplinary teams, and balance concurrent project tasks in alignment with demanding schedules and budgets.

         Reliably maintained complete and accurate laboratory documentation and electronic files.

         Skilled in using word processing, spreadsheets, graphical and presentation software applications.

Freeport-McMoRan, Sierrita 2015 to Present

Laboratory Technician II

         Proficiently operate SPECTRO ARCOS and SPECTRO CIRCOS ICP-OES, Perkin Elmer PinAAcle AA, LECO TCH 600 and LECO SC632 in a production analytical lab environment supporting FMI Mill, Moly, and Metallurgical departments.

         Diligently ensure assays comply with high quality standards for product shipments to customers including rhenium, molybdenum sulfide and molybdenum oxide products.

         Contribute to preparation of all samples going to Sierrita lab.

         Exercise sharp organizational skills to compose technical reports, summaries, protocols and quantitative analyses.

         Use StarLims V10 software to optimize data processing, storage, retrieval and analysis.

         Facilitate and observe froth flotation processes of copper and molybdenum concentrator.

         Investigate and locate scientific literature to gain general and specific information.

University of Arizona, Tucson AZ, 2000 to 2015

Assistant Scientific Investigator, Cellular and Molecular Medicine (2010 to 2015)

         Spearheaded experiments involving in vitro and in vivo models of cardiac disease and efficiently compiled tables, graphs, and reports summarizing results.

         As Laboratory Manager, trained and scheduled staff, maintained lab equipment and instrumentation, replenished inventory, and enforced strict compliance with OSHA, NIH, and CDC guidelines.

         As Occupational Safety Designee, successfully guided facility in passing chemical, biological, and IACUC inspections for the last three years.

         Championed collection of experimental data that was instrumental to department securing a $1.5M NIH grant.

Senior Research Specialist, Arthritis Center (2008 to 2010)

         Conducted molecular and cellular analysis of T cells and dendritic cells treated in vitro with Plaquenil and interferon beta, prepared samples, and documented analytical findings.

         Applied solid leadership talents toward training and mentoring personnel, maintaining and calibrating laboratory equipment, and contributing critical experimental data which resulted in obtaining an NIH grant.

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Professional Experience continued Yyyyyy x. yyyyyy Page 2 of 2

Senior Research Specialist, Department of Surgery (2006 to 2007)

         Actively supported and advanced complex research efforts and executed experiments and procedures involving myocardial rescue with allogeneic stem cells in transgenic murine models.

         Consistently aimed to identify and implement improvements to lab processes and environment.

Senior Research Specialist, Gastroenterology & Hepatology (2004 to 2006)

         Independently planned, designed, and implemented protocols to explore acetaminophen hepatotoxicity and inflammation.

         Leveraged polished communication skills to author seven publications in peer-reviewed journals.

         Employed histology and immunofluorescence techniques to perform bench experiments, and documented results.

         Troubleshot issues, drove correction action, and maintained meticulous records.

Research Specialist, Arizona Cancer Center (2000 to 2003)

         Standardized experimental procedures to formulate dendritic cell-tumor cell hybrids for clinical vaccine application.

         Co-developed and maintained Good Laboratory Practices (GLPs) in precise alignment with FDA guidelines to ensure high-quality and reliable test data.

         Carried out well-structured bench experiments to generate hybrids and objectively validated their efficacy.

         Collaboratively designed a cleanroom according to GMP guidelines for vaccine manufacturing.

Bachelor of Science, Molecular and Cellular Biology

University of Arizona, Tucson, AZ, 2015

Pappas CT, Mayfield RM, Henderson C, Jamilpour N, Cover C, Hernandez Z, Hutchinson KR, Chu M, Nam KH, Valdez JM, Wong PK, Granzier HL, Gregorio CC. Knockout of Lmod2 results in shorter thin filaments followed by dilated cardiomyopathy and juvenile lethality. Proc Natl Acad Sci U S A. 2015 Oct 20.

Whitman SA, Cover C, Yu L, Nelson DL, Zarnescu DC, Gregorio CC. Desmoplakin and talin2 are novel mRNA targets of fragile X-related protein-1 in cardiac muscle. Circ Res. 2011 Jul 22; 109 (3):262-71.

Bajt ML, Cover C, Lemasters JJ Jaeschke H. Nuclear translocation of endonuclease G and apoptosis-inducing factor during acetaminophen-induced liver cell injury. Toxicol Sci. 2006 Nov; 94(1):217-25.

Cover C, Liu J, Farhood A, Malle E, Waalkes MP, Bajt ML, Jaeschke H, Pathophysiological role of the acute inflammatory response during Acetaminophen hepatotoxicity. Toxicol. Appl Pharmacol. 2006 Oct 1; 216(1):98-107.

Ito Y, Abril ER, Bethea NW, McCuskey MK, Cover C, Jaeschke H, Mccuskey RS. Mechanisms and pathophysiological implications of sinusoidal endothelial cell gap formation following treatment with Galactosamine/endotoxin in mice. Am J Physiol Gastrointest Liver Physiol. 2006 Aug; 291(2): G211-8.

Fickert P, Wagner M, Marschall HU, Fuchsbichler A, Zollner G,Tsybrovskyy O, Zatloukal K, Liu J, Waalkes MP, Cover

C,Denk H, Hofmann AF, Jaeschke H, Trauner M. 24-norUrsodeoxycholic acid is superior to ursodeoxycholic acid in the treatment of sclerosing cholangitis in Mdr2 (Abcb4) knockout mice. Gastroenterology. 2006 Feb; 130(2): 465-81.

Jaeschke H, Cover C, Bajt ML. Role of caspases in acetaminophen-induced liver injury. Life sci. 2006 Mar 6; 78(15):1670-6.

Cover C, Mansouri A, Knight TR, Bajt ML, Lemasters JJ, Pessayre D, Jaeschke H. Peroxynitrite-induced mitochondrial and endonuclease-mediated nuclear DNA damage in acetaminophen hepatotoxicity. J Pharmacol exp Ther. 2005 Nov; 315(2): 879-87.

Cover C, Fickert P, Knight TR, Fuchsbichler A, Farhood A, Trauner M, Jaeschke H. Pathophysiological role of poly (ADP-ribose) polymerase (PARP) activation during acetaminophen-induced liver cell necrosis in mice. Toxicol Sci. 2005 Mar; 84(1): 201-8.

Trevor KT, Cover C, Ruiz YW, Akporiaye ET, Hersh EM, Landais D, Taylor RR, King AD, Walters RE. Generation of dendritic cell-tumor cell hybrids by electrofusion for clinical Vaccine application. Cancer Immunol Immunother. 2004 Aug; 53(8): 705-14.